Dennis S. Charney, MD is Dean of Mount Sinai School of Medicine and Executive Vice President for Academic Affairs of The Mount Sinai Medical Center.

Dr. Charney is a world expert in the neurobiology and treatment of mood and anxiety disorders. He has made fundamental contributions to the understanding of neural circuits and neurochemistry related to human anxiety, fear, mood as well AS THE discovery of new treatment for mood and anxiety disorders. He later expanded this area into pioneering research related to the psychobiological mechanisms of human resilience to stress.

Early in his career, Dr. Charney led a team that determined that the biology of human anxiety disorders were characterized by excessive noradrenergic activity and dysfunction in specific neural circuits including the prefrontal cortex, amygdala, and hippocampus. His work in depression led to new hypotheses regarding the mechanisms of antidepressant drugs and discovery of new and novel therapies for treatment resistant depression including Lithium and Ketamine, which works within hours.

After decades of work on the biology of anxiety, depression, and post traumatic stress disorder (PTSD), Dr. Charney and colleagues have turned their attention toward investigating the psychobiological mechanisms of human resilience to stress. They have found specific hormones and peptides which contribute to resilience and identified a prescription for enhancing human resilience.

A prolific author, Dr. Charney has written more than 700 publications, including groundbreaking scientific papers, chapters, and books. Dr. Charney’s most recent book is Resilience: The Science of Mastering Life’s Greatest Challenges.

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David Van Nuys, PhD
Creator/Host of Shrink Rap Radio

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